Small molecules which reverse IGF1 KO
Canned Analysis
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General Information
AccessionDCA00020302
TitleSmall molecules which reverse IGF1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IGF1 KO in the vestibular organ, day E18.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22feee467bea600fbb662
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1318
Cell Typevestibular organ, day E18.5
Gene Symbol (human)IGF1
Gene Symbol (mouse)Igf1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1589481, GSM1589482, GSM1589483
Perturbed SamplesGSM1589478, GSM1589479, GSM1589480
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE65202
Gene Expression Omnibus
Gene expression study of developing mammalian vestibular organ of wild type and Insulin-Like Growth Factor I deficient mice using Affymetrix whole tra...
21
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