Small molecules which reverse MAPK7 KD
Canned Analysis
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General Information
AccessionDCA00020310
TitleSmall molecules which reverse MAPK7 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAPK7 KD in the MCF-7 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d201d4e467bea600fba248
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDgene:1807
Cell TypeMCF-7
Gene Symbol (human)MAPK7
Gene Symbol (mouse)Mapk7
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1290793, GSM1290794
Perturbed SamplesGSM1290797, GSM1290798
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53394
Gene Expression Omnibus
17-estradiol effect on breast adenocarcinoma cells deficient in extracellular signal-regulated kinase 5
21
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