Small molecules which mimic SMARCA4 KD
Canned Analysis
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General Information
AccessionDCA00020315
TitleSmall molecules which mimic SMARCA4 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SMARCA4 KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f16ee467bea600fb9b5a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1324
Cell TypeES cells
Gene Symbol (human)SMARCA4
Gene Symbol (mouse)Smarca4
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM768325, GSM768326
Perturbed SamplesGSM768355, GSM768356
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE31008
Gene Expression Omnibus
A key role for Mbd3 in 5-hydroxymethylcytosine-dependent gene regulation in embryonic stem cells
28
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