Small molecules which reverse POU5F1 KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020322
TitleSmall molecules which reverse POU5F1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by POU5F1 KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f1b2e467bea600fb9b78
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1329
Cell TypeES cells
Gene Symbol (human)POU5F1
Gene Symbol (mouse)Pou5f1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM528605, GSM528607, GSM528611
Perturbed SamplesGSM528606, GSM528608, GSM528612
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21135
Gene Expression Omnibus
OCT4 Knockdown in human embryonic stem cells
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.