Small molecules which mimic REST KD
Canned Analysis
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General Information
AccessionDCA00020325
TitleSmall molecules which mimic REST KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by REST KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23b3de467bea600fbbb58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1331
Cell TypeES cells
Gene Symbol (human)REST
Gene Symbol (mouse)Rest
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM697129, GSM697130, GSM697131
Perturbed SamplesGSM697132, GSM697133, GSM697134
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE28141
Gene Expression Omnibus
Genome-wide analysis of REST knockdown responsive gene expression in mouse ES cells
7
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