Small molecules which mimic PCGF6 KD
Canned Analysis
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General Information
AccessionDCA00020343
TitleSmall molecules which mimic PCGF6 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PCGF6 KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2202ce467bea600fbaf6c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1340
Cell TypeES cells
Gene Symbol (human)PCGF6
Gene Symbol (mouse)Pcgf6
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1356254, GSM1356256
Perturbed SamplesGSM1356253, GSM1356255
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE56126
Gene Expression Omnibus
PCGF6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ES cells and functions in iPS reprogramming
7
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