Small molecules which mimic AURKA KD
Canned Analysis
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General Information
AccessionDCA00020357
TitleSmall molecules which mimic AURKA KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by AURKA KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22064e467bea600fbaf84
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1348
Cell TypeES cells
Gene Symbol (human)AURKA
Gene Symbol (mouse)Aurka
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM577216, GSM577217, GSM577218, GSM577240, GSM577241, GSM577242
Perturbed SamplesGSM577213, GSM577214, GSM577215
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23541
Gene Expression Omnibus
Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling
7
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