Small molecules which reverse SOX2 KD
Canned Analysis
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General Information
AccessionDCA00020364
TitleSmall molecules which reverse SOX2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SOX2 KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d219a2e467bea600fbacc2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1351
Cell TypeES cells
Gene Symbol (human)SOX2
Gene Symbol (mouse)Sox2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM857336, GSM857337, GSM857338, GSM857339, GSM857340
Perturbed SamplesGSM857360, GSM857361, GSM857362, GSM857363, GSM857364
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34904
Gene Expression Omnibus
NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 1)
21
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