Small molecules which reverse TET1 KD
Canned Analysis
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General Information
AccessionDCA00020368
TitleSmall molecules which reverse TET1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TET1 KD in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d219b4e467bea600fbacca
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1353
Cell TypeES cells
Gene Symbol (human)TET1
Gene Symbol (mouse)Tet1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM659775, GSM659776, GSM659777, GSM659778
Perturbed SamplesGSM659779, GSM659780, GSM659781, GSM659782
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE26830
Gene Expression Omnibus
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells (mRNA)
7
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