Small molecules which mimic TRNP1 KD
Canned Analysis
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General Information
AccessionDCA00020409
TitleSmall molecules which mimic TRNP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TRNP1 KD in the embryonic cerebral cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d225d6e467bea600fbb1e8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1375
Cell Typeembryonic cerebral cortex
Gene Symbol (human)TRNP1
Gene Symbol (mouse)Trnp1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM997203, GSM997204, GSM997205
Perturbed SamplesGSM997207, GSM997208, GSM997209
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE40582
Gene Expression Omnibus
TRNP1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate
7
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