Small molecules which reverse RNF40 KD
Canned Analysis
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General Information
AccessionDCA00020426
TitleSmall molecules which reverse RNF40 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RNF40 KD in the adiposcyte differentiation of hMSCs (5 days) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20882e467bea600fba53a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1386
Cell Typeadiposcyte differentiation of hMSCs (5 days)
Gene Symbol (human)RNF40
Gene Symbol (mouse)Rnf40
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM936239, GSM936240, GSM936241
Perturbed SamplesGSM936254, GSM936255, GSM936256
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38173
Gene Expression Omnibus
The Histone H2B Monoubiquitination Regulatory Pathway is Required for Differentiation of Multipotent Stem Cells
35
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