Small molecules which reverse DDIT3 knock-out (treated with 2 ug/ml tunicamycin for 4 hours)
Canned Analysis
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General Information
AccessionDCA00020432
TitleSmall molecules which reverse DDIT3 knock-out (treated with 2 ug/ml tunicamycin for 4 hours)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DDIT3 knock-out (treated with 2 ug/ml tunicamycin for 4 hours) in the embryonic fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2088ce467bea600fba53e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1387
Cell Typeembryonic fibroblasts
Gene Symbol (human)DDIT3
Gene Symbol (mouse)Ddit3
Organismmouse
Perturbation Typeknock-out (treated with 2 ug/ml tunicamycin for 4 hours)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM37661, GSM37662, GSM37663, GSM37664
Perturbed SamplesGSM37665, GSM37666, GSM37667, GSM37668
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2082
Gene Expression Omnibus
Transcription factor CHOP null mutation effect on fibroblasts subjected to ER stress: time course
21
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