Small molecules which reverse SALL4 KD
Canned Analysis
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General Information
AccessionDCA00020448
TitleSmall molecules which reverse SALL4 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SALL4 KD in the SNU-398, Hepatocellular carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2271de467bea600fbb27a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1408
Cell TypeSNU-398, Hepatocellular carcinoma cell line
Gene Symbol (human)SALL4
Gene Symbol (mouse)Sall4
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM878160, GSM878161, GSM878162
Perturbed SamplesGSM878163, GSM878164, GSM878165
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35965
Gene Expression Omnibus
A novel role of stem cell factor SALL4 as an oncofetal protein in hepatocellular carcinoma
7
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