Small molecules which reverse EZH2 DEPLETION
Canned Analysis
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General Information
AccessionDCA00020476
TitleSmall molecules which reverse EZH2 DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EZH2 DEPLETION in the embryonic fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20f7ce467bea600fba852
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:144
Cell Typeembryonic fibroblasts
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismhuman
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM139762, GSM139763, GSM139764
Perturbed SamplesGSM139677, GSM139678, GSM139679
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6015
Gene Expression Omnibus
Polycomb group protein depletion effect on embryonic fibroblasts
28
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