Small molecules which mimic KLF5 KO
Canned Analysis
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General Information
AccessionDCA00020489
TitleSmall molecules which mimic KLF5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KLF5 KO in the LSK cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23029e467bea600fbb67c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1427
Cell TypeLSK cells
Gene Symbol (human)KLF5
Gene Symbol (mouse)Klf5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1071463, GSM1071464, GSM1071465, GSM1071466, GSM1071467, GSM1071468
Perturbed SamplesGSM1071458, GSM1071459, GSM1071460, GSM1071461, GSM1071462
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43806
Gene Expression Omnibus
Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated membrane Beta1/Beta2-integrin expression
7
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