Small molecules which reverse DUX4 OE
Canned Analysis
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General Information
AccessionDCA00020494
TitleSmall molecules which reverse DUX4 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DUX4 OE in the primary myoblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d230b0e467bea600fbb6b6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1429
Cell Typeprimary myoblasts
Gene Symbol (human)DUX4
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM836025, GSM836026, GSM836027, GSM836028
Perturbed SamplesGSM836021, GSM836022
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33799
Gene Expression Omnibus
DUX4 activates germline genes, retroelements and immune-mediators: Implications for facioscapulohumeral dystrophy
14
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