Small molecules which mimic DUX4 OE
Canned Analysis
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General Information
AccessionDCA00020495
TitleSmall molecules which mimic DUX4 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DUX4 OE in the primary myoblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2358de467bea600fbb8da
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1430
Cell Typeprimary myoblasts
Gene Symbol (human)DUX4
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM836025, GSM836026, GSM836027, GSM836028
Perturbed SamplesGSM836023, GSM836024
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33799
Gene Expression Omnibus
DUX4 activates germline genes, retroelements and immune-mediators: Implications for facioscapulohumeral dystrophy
14
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