Small molecules which reverse FOXP1 KD
Canned Analysis
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General Information
AccessionDCA00020504
TitleSmall molecules which reverse FOXP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FOXP1 KD in the memory B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d235b4e467bea600fbb8ec
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1435
Cell Typememory B cells
Gene Symbol (human)FOXP1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1244383, GSM1244385, GSM1244387
Perturbed SamplesGSM1244384, GSM1244386, GSM1244388
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51382
Gene Expression Omnibus
Retroviral overexpression or siRNA mediated knockdown of FOXP1 in DLBCL cell lines and primary human B cells
28
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