Small molecules which reverse XBP1 OE
Canned Analysis
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General Information
AccessionDCA00020512
TitleSmall molecules which reverse XBP1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by XBP1 OE in the adipocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d235c6e467bea600fbb8f4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1437
Cell Typeadipocyte
Gene Symbol (human)XBP1
Gene Symbol (mouse)Xbp1
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1125686, GSM1125687, GSM1125688
Perturbed SamplesGSM1125690, GSM1125691, GSM1125692
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46178
Gene Expression Omnibus
X-box binding protein 1 overexpression effect on adipocyte cell line
14
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