Small molecules which reverse RAP1A KO
Canned Analysis
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General Information
AccessionDCA00020526
TitleSmall molecules which reverse RAP1A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RAP1A KO in the white adipose tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23be5e467bea600fbbba6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1443
Cell Typewhite adipose tissue
Gene Symbol (human)RAP1A
Gene Symbol (mouse)Rap1a
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1126365, GSM1126366, GSM1126367
Perturbed SamplesGSM1126368, GSM1126369, GSM1126370
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE46209
Gene Expression Omnibus
Non-telomeric role for Rap1 in regulating metabolism and protecting against obesity
28
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