Small molecules which reverse HPRT1 KO
Canned Analysis
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General Information
AccessionDCA00020540
TitleSmall molecules which reverse HPRT1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HPRT1 KO in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f229e467bea600fb9bac
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1450
Cell TypeES cells
Gene Symbol (human)HPRT1
Gene Symbol (mouse)Hprt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM570862, GSM570863
Perturbed SamplesGSM570858, GSM570859
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48790
Gene Expression Omnibus
Expression data from GTF2i mutated ES cells
21
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