Small molecules which reverse DGCR8 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020552
TitleSmall molecules which reverse DGCR8 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DGCR8 KO in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f1f3e467bea600fb9b94
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1456
Cell TypeES cells
Gene Symbol (human)DGCR8
Gene Symbol (mouse)Dgcr8
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM424460, GSM424461, GSM424462
Perturbed SamplesGSM424463, GSM424464, GSM424465
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16923
Gene Expression Omnibus
Expression data from wild-type, Dgcr8 knockout and Dicer knockout ES cells
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.