Small molecules which reverse CTNNB1 KO
Canned Analysis
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General Information
AccessionDCA00020556
TitleSmall molecules which reverse CTNNB1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 KO in the embryonic pancreas, day E14.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f6a9e467bea600fb9da0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1462
Cell Typeembryonic pancreas, day E14.5
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM177400, GSM177401
Perturbed SamplesGSM177393, GSM177397, GSM177398, GSM177399
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7430
Gene Expression Omnibus
Investigate the role of Wnt/beta-catenin signaling in development of the exocrine pancreas
7
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