Small molecules which reverse AHR KO
Canned Analysis
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General Information
AccessionDCA00020566
TitleSmall molecules which reverse AHR KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by AHR KO in the melanocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2285de467bea600fbb30a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1468
Cell Typemelanocytes
Gene Symbol (human)AHR
Gene Symbol (mouse)Ahr
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM482771, GSM482772
Perturbed SamplesGSM482773, GSM482774
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19411
Gene Expression Omnibus
Expression data of primary melanocytes from aryl hydrocarbon deficient mice and corresponding wild-type C57BL/6 mice
7
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