Small molecules which mimic PDSS2 KO
Canned Analysis
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General Information
AccessionDCA00020567
TitleSmall molecules which mimic PDSS2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PDSS2 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20f8ce467bea600fba858
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:147
Cell Typeliver
Gene Symbol (human)PDSS2
Gene Symbol (mouse)Pdss2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM276436, GSM276437, GSM276438
Perturbed SamplesGSM276433, GSM276434, GSM276435
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10904
Gene Expression Omnibus
Murine model of primary mitochondrial dysfunction
7
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