Small molecules which mimic MET KO
Canned Analysis
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General Information
AccessionDCA00020597
TitleSmall molecules which mimic MET KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MET KO in the FACS purified YFP+ muscle stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f9bae467bea600fb9eba
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1485
Cell TypeFACS purified YFP+ muscle stem cells
Gene Symbol (human)MET
Gene Symbol (mouse)Met
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1338079, GSM1338080, GSM1338081, GSM1338082, GSM1338083
Perturbed SamplesGSM1338096, GSM1338097, GSM1338098, GSM1338099
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55490
Gene Expression Omnibus
mTORC1 controls the systemically-induced adaptive regulation of stem cell quiescence into GAlert
21
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