Small molecules which mimic ZFX KO
Canned Analysis
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General Information
AccessionDCA00020603
TitleSmall molecules which mimic ZFX KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ZFX KO in the MLL-AF9 AML cell line 10980 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fff1e467bea600fba172
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1491
Cell TypeMLL-AF9 AML cell line 10980
Gene Symbol (human)ZFX
Gene Symbol (mouse)Zfx
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM906327, GSM906329, GSM906331, GSM906333, GSM906335
Perturbed SamplesGSM906328, GSM906330, GSM906332, GSM906334, GSM906336
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36921
Gene Expression Omnibus
Effect of genetic Zfx deletion on gene expression in c-Kit + MLL-AF9 AML cells
7
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