Small molecules which reverse NF1 KO
Canned Analysis
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General Information
AccessionDCA00020608
TitleSmall molecules which reverse NF1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NF1 KO in the Analysis of triceps muscles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ffe1e467bea600fba16c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:1493
Cell TypeAnalysis of triceps muscles
Gene Symbol (human)NF1
Gene Symbol (mouse)Nf1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM725364, GSM725365, GSM725366, GSM725367
Perturbed SamplesGSM725368, GSM725369, GSM725370, GSM725371
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29343
Gene Expression Omnibus
Neurofibromin inactivation effect on triceps muscle
12
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