Small molecules which reverse BAP1 KO
Canned Analysis
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General Information
AccessionDCA00020612
TitleSmall molecules which reverse BAP1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BAP1 KO in the Clear-cell renal cell carcinoma tumor (VHL inactivated) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20017e467bea600fba184
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1495
Cell TypeClear-cell renal cell carcinoma tumor (VHL inactivated)
Gene Symbol (human)BAP1
Gene Symbol (mouse)Bap1
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM904989, GSM905002, GSM905009, GSM905014, GSM905020, GSM905023, GSM905029, GSM905034
Perturbed SamplesGSM905004, GSM905024, GSM905038, GSM905043
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36895
Gene Expression Omnibus
Clear-cell renal cell carcinoma tumors and tumorgrafts deficient for tumor suppressor BAP1 or PBRM1
21
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