Small molecules which reverse GNMT KO
Canned Analysis
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General Information
AccessionDCA00020616
TitleSmall molecules which reverse GNMT KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GNMT KO in the Sciatic nerves cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fffde467bea600fba178
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1496
Cell TypeSciatic nerves
Gene Symbol (human)GNMT
Gene Symbol (mouse)Gnmt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1112072, GSM1112073
Perturbed SamplesGSM1112070, GSM1112071
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE45701
Gene Expression Omnibus
DNA methylation status of myelinating Schwann cells during development and in diabetic neuropathy [Gene Expression Array: GNMT mice]
7
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