Small molecules which reverse DICER1 KO
Canned Analysis
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General Information
AccessionDCA00020626
TitleSmall molecules which reverse DICER1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DICER1 KO in the Sarcoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d220a6e467bea600fbafa2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1501
Cell TypeSarcoma cell line
Gene Symbol (human)DICER1
Gene Symbol (mouse)Dicer1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1079827, GSM1079828, GSM1079829
Perturbed SamplesGSM1079830, GSM1079831, GSM1079832
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44162
Gene Expression Omnibus
Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [3p arrays]
7
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