Small molecules which mimic JUN Overexpression of a dominant negative form
Canned Analysis
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General Information
AccessionDCA00020633
TitleSmall molecules which mimic JUN Overexpression of a dominant negative form
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by JUN Overexpression of a dominant negative form in the Liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d220bde467bea600fbafac
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1505
Cell TypeLiver tissue
Gene Symbol (human)JUN
Gene Symbol (mouse)Jun
Organismmouse
Perturbation TypeOverexpression of a dominant negative form
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM157850, GSM157857, GSM157858, GSM157859, GSM157860
Perturbed SamplesGSM157861, GSM157862, GSM157863, GSM157864, GSM157865
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6850
Gene Expression Omnibus
Dominant negative cJun effect on apolipoprotein E deficient livers
7
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