Small molecules which mimic XBP1 expression of XBP1s, an spliced version of the protein
Canned Analysis
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General Information
AccessionDCA00020637
TitleSmall molecules which mimic XBP1 expression of XBP1s, an spliced version of the protein
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by XBP1 expression of XBP1s, an spliced version of the protein in the splenic B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d220cfe467bea600fbafb4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:1507
Cell Typesplenic B cells
Gene Symbol (human)XBP1
Gene Symbol (mouse)Xbp1
Organismmouse
Perturbation Typeexpression of XBP1s, an spliced version of the protein
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM160730, GSM160731, GSM160739, GSM160860, GSM160861
Perturbed SamplesGSM160864, GSM160865, GSM160866, GSM160867, GSM160868
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6980
Gene Expression Omnibus
Multiple myeloma model
14
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