Small molecules which mimic POLG Mutation
Canned Analysis
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General Information
AccessionDCA00020641
TitleSmall molecules which mimic POLG Mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by POLG Mutation in the Analysis of cochleas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21a20e467bea600fbacf8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:1515
Cell TypeAnalysis of cochleas
Gene Symbol (human)POLG
Gene Symbol (mouse)Polg
Organismmouse
Perturbation TypeMutation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM109462, GSM109463, GSM109464, GSM109465, GSM109466
Perturbed SamplesGSM109467, GSM109468, GSM109470, GSM109471, GSM109472
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4866
Gene Expression Omnibus
Cochlea response to mitochondrial DNA mutations
7
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