Small molecules which reverse FH KD
Canned Analysis
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General Information
AccessionDCA00020648
TitleSmall molecules which reverse FH KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FH KD in the Uterine fibroid tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21a11e467bea600fbacf2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1517
Cell TypeUterine fibroid tissue
Gene Symbol (human)FH
Gene Symbol (mouse)Fh1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM52678, GSM52680
Perturbed SamplesGSM52673, GSM52674, GSM52675, GSM52676, GSM52677
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2725
Gene Expression Omnibus
Uterine fibroids with mutated fumarate hydratase (II)
14
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