Small molecules which mimic PHGDH KO
Canned Analysis
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General Information
AccessionDCA00020657
TitleSmall molecules which mimic PHGDH KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PHGDH KO in the embryonic head tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21534e467bea600fbaacc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:152
Cell Typeembryonic head tissue
Gene Symbol (human)PHGDH
Gene Symbol (mouse)Phgdh
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM212558, GSM212560, GSM212562, GSM212564
Perturbed SamplesGSM212559, GSM212561, GSM212563, GSM212565
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8555
Gene Expression Omnibus
D-3-phosphoglycerate dehydrogenase deficiency effect on the embryonic head
7
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