Small molecules which reverse IRF6 KO
Canned Analysis
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General Information
AccessionDCA00020670
TitleSmall molecules which reverse IRF6 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IRF6 KO in the skin E17.5 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2152ee467bea600fbaaca
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:153
Cell Typeskin E17.5
Gene Symbol (human)IRF6
Gene Symbol (mouse)Irf6
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM135473, GSM135474, GSM135475
Perturbed SamplesGSM135470, GSM135471, GSM135472
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5800
Gene Expression Omnibus
Interferon regulatory factor 6 null mutation effect on the skin
7
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