Small molecules which mimic APC KD
Canned Analysis
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General Information
AccessionDCA00020675
TitleSmall molecules which mimic APC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by APC KD in the Ileum epithelials cells (carcinoma) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20e2be467bea600fba7bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1532
Cell TypeIleum epithelials cells (carcinoma)
Gene Symbol (human)APC
Gene Symbol (mouse)Apc
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM6191, GSM6192, GSM6193, GSM6194, GSM6195, GSM6196
Perturbed SamplesGSM6202, GSM6203, GSM6204, GSM6205, GSM6206
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE422
Gene Expression Omnibus
Colon cancer
36
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