Small molecules which reverse APC APC(Min/+) mutant
Canned Analysis
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General Information
AccessionDCA00020678
TitleSmall molecules which reverse APC APC(Min/+) mutant
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by APC APC(Min/+) mutant in the Intestinal epithelia cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20531e467bea600fba3c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:1732
Cell TypeIntestinal epithelia
Gene Symbol (human)APC
Gene Symbol (mouse)Apc
Organismmouse
Perturbation Type APC(Min/+) mutant
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM6191, GSM6192, GSM6193, GSM6194, GSM6195, GSM6196
Perturbed SamplesGSM6197, GSM6198, GSM6199, GSM6200, GSM6201, GSM6202, GSM6203, GSM6204, GSM6205, GSM6206
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE422
Gene Expression Omnibus
Colon cancer
36
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