Small molecules which reverse HOXA10 KO
Canned Analysis
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General Information
AccessionDCA00020684
TitleSmall molecules which reverse HOXA10 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HOXA10 KO in the total uterus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20e37e467bea600fba7c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1535
Cell Typetotal uterus
Gene Symbol (human)HOXA10
Gene Symbol (mouse)Hoxa10
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM3044, GSM3045, GSM3046
Perturbed SamplesGSM3050, GSM3051, GSM3052
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6439
Gene Expression Omnibus
Progesterone and Hoxa-10 relationship
7
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