Small molecules which reverse IL10 KO
Canned Analysis
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General Information
AccessionDCA00020694
TitleSmall molecules which reverse IL10 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IL10 KO in the Lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d210d1e467bea600fba8e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgregmicrotask
CREEDS IDgene:1831
Cell TypeLung
Gene Symbol (human)IL10
Gene Symbol (mouse)Il10
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM616484, GSM616485, GSM616486
Perturbed SamplesGSM616481, GSM616482, GSM616483
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25095
Gene Expression Omnibus
Ozone effect on Interleukin-10 deficient lung: time course
28
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