Small molecules which mimic SP3 KD
Canned Analysis
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General Information
AccessionDCA00020707
TitleSmall molecules which mimic SP3 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SP3 KD in the Jurkat T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23544e467bea600fbb8ba
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1548
Cell TypeJurkat T cells
Gene Symbol (human)SP3
Gene Symbol (mouse)Sp3
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM170817, GSM170818, GSM170821, GSM170822, GSM170824, GSM170825
Perturbed SamplesGSM170826, GSM170827, GSM170829, GSM170830, GSM170831, GSM170832
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7102
Gene Expression Omnibus
siRNA-mediated knockdown of Sp3 induces a pro-inflammatory pattern of cytokine production: relevance to MS
7
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