Small molecules which reverse HDAC3 Intestinal Epithelial Cells specific deletion of HDAC3
Canned Analysis
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General Information
AccessionDCA00020712
TitleSmall molecules which reverse HDAC3 Intestinal Epithelial Cells specific deletion of HDAC3
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HDAC3 Intestinal Epithelial Cells specific deletion of HDAC3 in the Intestinal Epithelial Cells from large intestine cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23b08e467bea600fbbb42
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1550
Cell TypeIntestinal Epithelial Cells from large intestine
Gene Symbol (human)HDAC3
Gene Symbol (mouse)Hdac3
Organismmouse
Perturbation TypeIntestinal Epithelial Cells specific deletion of HDAC3
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1215249, GSM1215250, GSM1215251
Perturbed SamplesGSM1215252, GSM1215253, GSM1215254
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50189
Gene Expression Omnibus
Regulation of gene expression in IECs by HDAC3 under germ-free conditions
7
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