Small molecules which mimic CLDN2 OE
Canned Analysis
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General Information
AccessionDCA00020713
TitleSmall molecules which mimic CLDN2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CLDN2 OE in the colon epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22f77e467bea600fbb62c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1551
Cell Typecolon epithelial cells
Gene Symbol (human)CLDN2
Gene Symbol (mouse)Cldn2
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1121628, GSM1121629, GSM1121630
Perturbed SamplesGSM1121631, GSM1121632, GSM1121633
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE46006
Gene Expression Omnibus
The Tight Junction Protein Claudin-2 Controls Mucosal Permeability, Immune Tolerance and Colitis in Mice
7
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