Small molecules which reverse MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
Canned Analysis
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General Information
AccessionDCA00020734
TitleSmall molecules which reverse MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MN1 reotrviral delivery of MN1 or MN1VP16 fusion for transcriptional in the C57BL/6J GFP+ bone marrow cells transduced with viral vector cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22fc1e467bea600fbb64e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1559
Cell TypeC57BL/6J GFP+ bone marrow cells transduced with viral vector
Gene Symbol (human)MN1
Gene Symbol (mouse)Mn1
Organismmouse
Perturbation Typereotrviral delivery of MN1 or MN1VP16 fusion for transcriptional
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1185232, GSM1185233
Perturbed SamplesGSM1185234, GSM1185235
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE48819
Gene Expression Omnibus
Gene expression changes induced by overexpression of MN1 and MN1VP16 in murine bone marrow cells
7
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