Small molecules which mimic KLF1 KO
Canned Analysis
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General Information
AccessionDCA00020741
TitleSmall molecules which mimic KLF1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KLF1 KO in the primitive erythroid precursors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22affe467bea600fbb434
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:1562
Cell Typeprimitive erythroid precursors
Gene Symbol (human)KLF1
Gene Symbol (mouse)Klf1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM893168, GSM893169, GSM893170, GSM893171, GSM893175, GSM893176, GSM893177, GSM893178
Perturbed SamplesGSM893172, GSM893173, GSM893174
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36427
Gene Expression Omnibus
KLF1, KLF2 and c-myc control a regulatory network essential for embryonic erythropoiesis
7
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