Small molecules which reverse PIAS1 KD
Canned Analysis
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General Information
AccessionDCA00020746
TitleSmall molecules which reverse PIAS1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PIAS1 KD in the breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b8ce467bea600fbad96
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormirobilis
CREEDS IDgene:160
Cell Typebreast cancer cells
Gene Symbol (human)PIAS1
Gene Symbol (mouse)Pias1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1076965, GSM1076966
Perturbed SamplesGSM1076967, GSM1076968
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44024
Gene Expression Omnibus
PIAS1 SUMO ligase depletion effect on breast cancer cell line
12
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