Small molecules which reverse PIAS1 Depletion
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020748
TitleSmall molecules which reverse PIAS1 Depletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PIAS1 Depletion in the MDA-MB 231 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f1c5e467bea600fb9b80
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:37
Cell TypeMDA-MB 231 breast cancer cells
Gene Symbol (human)PIAS1
Gene Symbol (mouse)Pias1
Organismhuman
Perturbation TypeDepletion
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1076967, GSM1076968
Perturbed SamplesGSM1076965, GSM1076966
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44024
Gene Expression Omnibus
PIAS1 SUMO ligase depletion effect on breast cancer cell line
12
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.