Small molecules which reverse BMPR1A KO
Canned Analysis
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General Information
AccessionDCA00020784
TitleSmall molecules which reverse BMPR1A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BMPR1A KO in the ES cells (N2B27 media) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20dbbe467bea600fba78a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1623
Cell TypeES cells (N2B27 media)
Gene Symbol (human)BMPR1A
Gene Symbol (mouse)Bmpr1a
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1168402, GSM1168403, GSM1168404
Perturbed SamplesGSM1168405, GSM1168406, GSM1168407
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48092
Gene Expression Omnibus
Profile of Bmpr1a-/- embryonic stem cells in ESC media and N2B27
14
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