Small molecules which mimic HTT KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020785
TitleSmall molecules which mimic HTT KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HTT KO in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20d8be467bea600fba774
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1624
Cell TypeES cells
Gene Symbol (human)HTT
Gene Symbol (mouse)Htt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM638129, GSM638130, GSM638131, GSM638132, GSM638133, GSM638134
Perturbed SamplesGSM638135, GSM638136, GSM638137, GSM638138, GSM638139, GSM638140
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE26001
Gene Expression Omnibus
Huntington's disease Hdh knock-out and knock-in embryonic stem cells
80
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.